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An electron scan showsthe HIV-1 virus budding (in green) from a white blood cell in a laboratory. |
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An HIV vaccine that could defeat the virus could undergo human trials in as little as a year's time, scientists say, the Daily Mail reported.
The "mosaic vaccine," which is being designed by an international team, is composed of many sets of synthetic, computer-generated sequences of proteins. These can cue the body's immune system to respond to a variety of HIV mutations.
HIV's ability to evolve rapidly is what allows it evade current drugs.
Bette Korber of the Los Alamos National Laboratory in New Mexico said researchers are in the evolutionary fast lane studying HIV. "If you give just one drug, HIV evolves away from it. That's why treatments involve three or four drugs at once," Korber said.
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艾滋病疫苗即將問世
??????? 英國《每日郵報(bào)》報(bào)道,科學(xué)家稱,可以戰(zhàn)勝致命的艾滋病病毒的疫苗最短一年后就可以進(jìn)行人體實(shí)驗(yàn)了。
???????這種由一個(gè)國際研究小組設(shè)計(jì)的“拼接疫苗”含有許多由計(jì)算機(jī)制造的合成蛋白質(zhì)序列,可以提示身體的免疫系統(tǒng)對(duì)艾滋病病毒的一系列變化作出反應(yīng)。
???????艾滋病病毒變化迅速,所以它可以避開現(xiàn)在的藥物。
???????新墨西哥州洛斯阿拉莫斯國家實(shí)驗(yàn)室的貝蒂·克勃說科學(xué)家對(duì)艾滋病病毒的研究正取得快速進(jìn)展。克勃說:“如果你僅僅用一種藥,艾滋病病毒很快就進(jìn)化了。這就是為什么治療總是需要同時(shí)用三四種藥。” |