Gerson and Federico Valverde scored second-half goals as Uruguay held Brazil to a 1-1 home draw in their World Cup qualifier on Tuesday.
Real Madrid midfielder Valverde gave the visitors the lead with an unstoppable long-range effort just before the hour.
The hosts equalized seven minutes later when Gerson used the outside of his left foot to smash home a first-time volley form 12 yards.
Brazil had more than 60 percent of possession and completed over 200 more passes than the Celeste but the five-time world champions paid the price for a lack of incisiveness in attack.
Dorival Junior's men dropped to fifth in the 10-team South American qualifying zone with 18 points, two points behind second-placed Uruguay.