Warner Bros. Pictures' comedy horror film "Beetlejuice Beetlejuice" dominated the North American box office with an estimated three-day cume of 110 million U.S. dollars on its opening weekend, data from the measurement firm Comscore showed on Sunday.

It's the second biggest opening weekend ever in North America in the month of September. The film also took in over 35.4 million dollars internationally for a global debut of 145.5 million dollars.

Directed by Tim Burton, the sequel to 1988's box office hit "Beetlejuice" stars Michael Keaton, Winona Ryder, and Catherine O'Hara reprising their roles alongside new cast members.

The film has earned an approval rating of 77 percent based on 243 reviews to date on the review-aggregation website Rotten Tomatoes, and a "B+" on an "A+" to "F" scale from audiences polled by the market research firm CinemaScore.

In second place, Marvel Studios' superhero film "Deadpool & Wolverine" showed staying power, pulling in 7.2 million dollars on its seventh weekend for a North American cume of 614 million dollars.

Historical biopic "Reagan," released by independent distributor ShowBiz Direct, landed in third place with 5.2 million dollars on its second weekend for a North American total of 18.5 million dollars through Sunday. 

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